12/18/2023 0 Comments 3d brain for pc![]() ![]() State-of-the-art glioma treatment includes a multi-disciplinary approach, combining surgical resection, chemotherapy, and radiation therapy. Although there have been great advances in glioma research, and treatment continues to evolve with new methods and strategies, gliomas remain a disease with poor prognosis. This diverse group of brain tumors comprises glioblastomas, astrocytomas, oligodendrogliomas, and ependymomas. Gliomas are the most frequent primary brain tumors in adults. Aiming for fast acquisition of quantitative MR biomarkers, 3D QTI has potential to improve disease characterization in brain tumor patients under tight clinical time-constraints. ConclusionģD QTI demonstrated comprehensive tissue assessment of tumor substructures captured in T1 and T2 parameters. Our study revealed increased T1 and T2 values in tumor and peritumoral regions compared to contralateral white matter, good agreement with healthy volunteer data, and high inter-subject consistency. The 3D acquisition combined with a compressed sensing reconstruction and neural network-based parameter inference produced parametric maps with high isotropic resolution (1.125 × 1.125 × 1.125 mm 3 voxel size) and whole-brain coverage (22.5 × 22.5 × 22.5 cm 3 FOV), enabling the synthesis of clinically relevant T1-weighted, T2-weighted, and FLAIR contrasts without any extra scan time. Second, for an initial assessment of 3D QTI-based quantitative MR biomarkers, we performed a ROI-based analysis to characterize T1 and T2 components in tumor and peritumoral tissue. ![]() First, we investigated the feasibility of 3D QTI (6:25 min scan time) for its use in clinical routine imaging, focusing on image reconstruction, parameter estimation, and contrast-weighted image synthesis. To demonstrate the viability of the proposed 3D QTI technique, nine glioma patients (grade II–IV), with a variety of disease states and treatment histories, were included in this study. ![]() In this study, we report initial clinical experience in routine glioma imaging with a novel, fully 3D multiparametric quantitative transient-state imaging (QTI) method for tissue characterization based on T1 and T2 values. Advanced MRI-based biomarkers offer comprehensive and quantitative information for the evaluation and characterization of brain tumors. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |